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  Ethionamide

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names


Systems General (Systemic)
Category Anti-tuberculous drug


Pharmacokinetics

The drug is rapidly absorbed from the GIT, completely metobolised in liver and is very well distributed throughout the body.



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Indications

Ethionamide is one of the drugs used in multiple drug treatment against tuberculosis (TB)



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Routes of Administration and Dosage

For oral dosage form (tablets): For the treatment of tuberculosis in Adults :500 to 750 mgs /day after food in 2 or 3 divided doses.In Children: Dose is based on body weight - 4 to 5 mg per kilogram of body weight every eight hours.



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Contra Indications

Ethionamide is contraindicated in hepatic disease and hypersensitivity.



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Precautions

Precaution to be taken in Diabetes mellitus where hyperglycemia is difficult to control, and in patients with psychiatric ilness.



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Interactions

When given with Cycloserine: the chance for adverse neurological effects, such as convulsions are increased.



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Brand Names

Ethide(Lupin), Ethiocid(Themis Chemicals), Ethomid(Macleods), Etomide(VHB), Mycotuf(Cadila Pharma), Myobid(Panacea).



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Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

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