Welcome, Guest    Sign in to Windows Live ID | Register  

  Industry Medical Portal |  Student Centre |  Sitemap |  Help 
FAQAbout Us |  Disclaimer & Legal |  Contact Us 

  Naproxen

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names


Systems Musculoskeletal System
Category NSAID-Propionic acid derivative.


Pharmacokinetics

Naproxen, when given orally is highly plasma protein bound. It gets metabolised in the liver. It has a t1/2 of 12-16 hrs.About 10% gets excreted in the urine. Naproxen enters the brain, synovial fluid and can cross the placenta.



Top

Indications

Naproxen is indicated in painful inflammatory conditions associated with the musculoskeletal system, dysmenorrhoea and also during post operative and post traumatic period. It is also given in chronic inflammatory condition like Rheumatoid arthritis, osteoarthritis



Top

Routes of Administration and Dosage

Oral: 250 mgs twice daily.



Top

Contra Indications

Naproxen is contraindicated in patients with known hypersensitivity, active peptic ulcer, moderate to severe hepatic disease and infants.



Top

Precautions

Precaution has to be taken in cardiac failure, edema, hypertention, elderly and in lactating women.



Top

Interactions

When Naproxen is used with lithium, Phenytoin, anticoagulants and Methotrexate it will increase their toxicity. It antagonises the effects of diuretics like Frusemide and Thiazides.



Top

Brand Names

Antesvel(Martel Hammer), Artagen(Ranbaxy), Movibon(Brown & Burk), Naprosyn(Searle), Napryn(Themis Pharma), Ralnep(Rallis), Xenobid(Rallis).



Top

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

|

 

Advertisement
Tell us what you think about Web Health Centre - Send us your feedback
Copyright © 2017 WebHealthCentre. All rights reserved. Brought to you by