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  Triamcinolone

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names


Systems General (Systemic)
Category Highly selective glucocorticoid.


Pharmacokinetics

The bio-availablity of Triamcinolone is moderately high after oral administration. It is rapidy absorbed orally. It is metabolised in the liver.



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Indications

Triamcinolone is used in allergies,bronchial asthma,dermatoses,rheumatoid arthritis and other connective tissue disorders. It is used as replacement therapy along with mineralocorticoids in steroid difficiency states.



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Routes of Administration and Dosage

Oral:4-32 mgs/day. 2.5-60mgs/day deep I.M. Intra-articular injection:2.5-15mg.



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Contra Indications

Triamcinolone is contraindicated in fungal infection, septic arthritis, herpes simplex, peptic ulcer and in glucocorticoid induced myopathy.



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Precautions

Special precautions have to be taken in diabetes, hypertension, CVS disease, renal impairment, glaucoma, elderly, neonates,psychosis and in hepatic cirrhosis.



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Interactions

Action blunted by barbiturates, phenytoin, rifampicin, cyclosporine and previous long term treatment with other corticosteroids. Absorption of triamcinolone is reduced by antacids. Triamcinolone antogonises the neuromuscular blockade by pancuronium.



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Brand Names

KENACORT[Sarabhai], LEDERCORT[Wyeth Lederle], PERICORT-4[Themis Chemicals], TRICORT[Alidac].



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Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

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