Welcome, Guest    Sign in to Windows Live ID | Register  

  Industry Medical Portal |  Student Centre |  Sitemap |  Help 
FAQAbout Us |  Disclaimer & Legal |  Contact Us 

  Vancomycin

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names


Systems Systemic (General)
Category Broad spectrum Antibiotic


Pharmacokinetics

Vancomycin is not absorbed orally and intramuscular injection is painful. It acts by inhibition of cell wall synthesis. It is mainly excreted via urine.



Top

Indications

Vancomycin acts against Gram positive cocci and is bactericidal. It acts on Methicillin resistant Staph.Aureus,Staph.epidermis, Strep.pyogenes, Strep.pneumoniae, Enteroccocus faecalis etc.



Top

Routes of Administration and Dosage

Oral dose (capsules, oral solution): For treatment of colitis or severe diarrhoea in Adults:125 to 500 milligrams (mg) every six hours for five to ten days. Children : 10 mg per kilogram (kg) of body weight, up to 125 mg. This dose is taken every six hours for five to ten days.Systemic 0.5 to 1 gram I.V b.d



Top

Contra Indications

Vancomycin is contraindicated in renal and auditory dysfunction.



Top

Precautions

Patients with Renal disease, inflammatory bowel disorders may have an increased chance of adverse effects. Rapid infusion may lead to sudden, profound fall in blood pressure, flushing,and itching (red man syndrome)



Top

Interactions

Cholestyramine, Colestipol : Use of these drugs with oral vancomycin may decrease the effects of oral vancomycin; oral vancomycin and these drugs should be taken several hours apart. Risk of increased nephrotoxicity with concommitant aminoglycosides. Neuromuscular blockade may occur if used together with non-depolarising agents.



Top

Brand Names

Vancocare(Criticare), Vancocin(Eli Lily Ranbaxy), Vancogen(Alkem), Vancoled(Wyeth Lederle), Vancorid CP(Panacea).



Top

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

|

 

Advertisement
Tell us what you think about Web Health Centre - Send us your feedback
Copyright © 2015 WebHealthCentre. All rights reserved. Brought to you by