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Home ›› Drug Guide ››Vitamin E (Alpha-Tocopherol) |
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Vitamin E (Alpha-Tocopherol)
Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names
Systems |
General (Systemic)
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Category |
Fat soluble vitamin.
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Pharmacokinetics
It is absorbed from the intestine through lymph. It circulates through the body plasma in association with Beta-lipoprotien. It is stored in the tissues and excreted as metabolites in the bile and urine.
Indications
Vitamin E is necessary in small amounts and is available in common foodstuffs like green leafy vegetables. Vitamin E prevents chemical oxidation, hence it acts mainly as an antioxidant. It is also important for the proper function of nerves and muscles. Vitamin E requirements are increased in intestinal disease, hepatic disease, pancreatic disorders and surgical removal of stomach.
Prolonged treatment with vitamin E increases the survival time of erythrocytes in G-6-PD deficiency. The risk of retrolental fibroplasia in infants exposed to high concentrations of oxygen can be reduced by oral vitamin E.
Routes of Administration and Dosage
Supplemental doses 10-30 mg/day may be given to patients at risk of developing deficiency. To increase the survival time of erythrocytes in G-6-PD deficiency: 100 mg/day of vitamin E should be given.The risk of retrolental fibroplasia in infants exposed t
Contra Indications
Vitamin E may be contraindicated in Bleeding disorders. It should not be administered I.V.
Precautions
Hypersensitivity reactions to the drug may occur. Precautions must be taken when taking the drug during pregnancy and breast-feeding.
Interactions
Interactions to this drug are usually rare. High doses potentiate the anticoagulant action of Warfarin.
Brand Names
COVITA (NEO PHARMA), ECAP (GLENMARK), EVION (MERCK), EVIT 200/400 (ABBOTT), NATVIE (FRANCO-INDIAN), VITEOLIN (GLAXO ALLENBURYS)
Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names
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